23484b
Seminar
S Molecular Biology of viruses and viral vectors
Stefan Weger
Information for students
Additional module information: Modulbeschreibung Molekulare Biologie viraler Erreger und Vektoren close
Additional information / Pre-requisites
Successful participation in the lecture in Winter Semester 2024/2025 is a prerequisite for participation in the seminar in Summer Semester 2025.
Comments
Content:
Subject of the seminar are the organization and structure of simple and complex DNA and RNA viruses, the function of various virus components, regulation of viral gene expression, mechanisms of viral genome replication, virus-host cell interaction, viral pathogenicity mechanisms and antiviral therapy. Based on original literature, similarities and overarching connections between individual virus families regarding viral genome replication, the regulation of gene expression, interference with cellular defense mechanisms and viral-induced oncogenesis are worked out and presented. A further important topic is the development and application of virus-based vectors for gene therapy applications.
Learning objectives:
After attending the module, the students have a broad range of theoretical knowledge about the molecular replication strategies of viruses, the mechanisms of virus-host cell interactions, the pathogenicity mechanisms of selected virus groups and the application of viral vectors in modern medicine. They are able to study, present and critically discuss original research papers. close
Subject of the seminar are the organization and structure of simple and complex DNA and RNA viruses, the function of various virus components, regulation of viral gene expression, mechanisms of viral genome replication, virus-host cell interaction, viral pathogenicity mechanisms and antiviral therapy. Based on original literature, similarities and overarching connections between individual virus families regarding viral genome replication, the regulation of gene expression, interference with cellular defense mechanisms and viral-induced oncogenesis are worked out and presented. A further important topic is the development and application of virus-based vectors for gene therapy applications.
Learning objectives:
After attending the module, the students have a broad range of theoretical knowledge about the molecular replication strategies of viruses, the mechanisms of virus-host cell interactions, the pathogenicity mechanisms of selected virus groups and the application of viral vectors in modern medicine. They are able to study, present and critically discuss original research papers. close