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L Frontiers in synthetic metabolism

Amelia Cox-Fermandois, Stefan Hristov, Lena Maria Hümmler, Jan Krüsemann, Dr. Steffen Lindner-Mehlich, Daniel Melnitchouk, Ehsan Salehabadi and members of the Lindlich Lab

Location: Seminarraum 3 (R 015) (Königin-Luise-Str. 12 / 16)

Schedule: 3. Block: 06.07. - 10.07.2026; daily; 12:30 - 16:30 AND 13.07. - 17.07.2026; daily; 12:30 - 14:30

Class starts on: 2026-07-06

Course language: English

Contact hours: 2

Number of participants: 20

Limited attendance: No

Attendance required: No

Modules where this course belongs:

Information for students

Additional module information: Frontiers in synthetic metabolism

For more information check out the website of the Lindlich Lab and for questions contact lena.huemmler(at)charite.de

Comments

Content:
Lecture: This course, taught by members of the Lindlich lab at Charité - Universitätsmedizin Berlin, introduces synthetic biology and metabolic engineering in bacteria. Students will learn why sustainable carbon sources are essential for future bioproduction and how molecular biology methods enable the construction of engineered metabolic pathways. They will also learn about the key challenges and goals of a sustainable bioeconomy and how they are being realised today. A central focus is the key technique used in the Lindlich lab: growth-coupling as a strategy for strain design and selection. The lectures also introduce computational approaches, including metabolic modeling and structural biology, to support rational engineering. .

Learning objectives:
Students will gain insight into prokaryotic synthetic metabolism with a focus on developing efficient biocatalysts for sustainable bioproduction. They will learn why replacing fossil-based processes with renewable and environmentally responsible alternatives is increasingly important, and how microorganisms can be used to achieve this. .

Module assessment: Students will prepare and present a journal club talk on a recent scientific publication and subsequently design and present a strategy for the biotechnological production of an interesting target compound.

10 Class schedule

Regular appointments

Mon, 2026-07-06 12:30 - 16:30

Lecturers:
Stefan Hristov
Ehsan Salehabadi
Lena Maria Hümmler
Amelia Eugenia Cox Fermandois
Daniel Melnitchouk
Jan Lukas Krüsemann
Steffen Lindner-Mehlich