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1. Role of microcirculation and ageing

Principal Investigators:

Prof. Dr. Petra Knaus (Freie Universität Berlin, Department of Biology, Chemistry, Pharmacy)

Dr. Richard Siow (King's College London, School of Cardiovascular Medicine & Sciences, FoLSM)

Collaborating Researchers:

Prof. Dr. Stephen Harridge (King's College London, Centre of Human & Aerospace Physiological Sciences & FoLSM)

Prof. Dr. Ulrich Keilholz (Charité - Universitätsmedizin Berlin, Charité Comprehensive Cancer Center)

Project Coordinator:

Dr. Gina Dörpholz (Freie Universität Berlin, Department of Biology, Chemistry, Pharmacy)

Project Summary:

The microvasculature is indispensable for transvascular exchange and fluid economy to e.g. provide oxygen and nutrients, to maintain vessel pressure and to avoid harmful flow disturbances. During ageing, the regenerative and angiogenic capacity of vascular cells is compromised eventually leading to tissue and end-organ dysfunction and thus diverse diseases and altered disease progression. The various in-/extrinsic factors and their complex interplay provoking ageing of the microvasculature still remain elusive.

Together with King's College London, we seek to organize joint research workshops and recruit third party funding applications. Thereby, we want to facilitate innovative top-level research in an international and interdisciplinary environment as well as to support young career researchers. Here, Dr. Gina Dörpholz, a biochemist by education, acts as scientific/proposal coordinator. She will support in coordinating workshops, is involved in proposal design and writing and coordinates the third party funding application process in close collaboration with all consortium members.